18-09-2010: 20e etappe San Martín de Valdeiglesias - Bola del Mundo 172,1 km
| Etappe uitslag |
| 1 | Ezequiel Mosquera |
| 2 | Vincenzo Nibali |
| 3 | Joaquin Rodriguez |
| 4 | Frank Schleck |
| 5 | Xavier Tondo |
| 6 | Nicolas Roche |
| 7 | Mikel Nieve |
| 8 | Peter Velits |
| 9 | Christophe Le Mével |
| 10 | Remy Di Gregorio |
| 11 | Carlos Sastre |
| 12 | Oscar Pujol |
| 13 | Hubert Dupont |
| 14 | Josep Jufre |
| 15 | Roman Kreuziger |
| Rode trui klassement |
| 1 | Vincenzo Nibali |
| 2 | Ezequiel Mosquera |
| 3 | Peter Velits |
| Groene trui klassement |
| 1 | Mark Cavendish |
| 2 | Tyler Farrar |
| 3 | Vincenzo Nibali |
| Bolletjes trui klassement |
| 1 | David Moncoutié |
| 2 | Serafin Martinez |
| 3 | Ezequiel Mosquera |
| Witte trui klassement |
| 1 | Vincenzo Nibali |
| 2 | Ezequiel Mosquera |
| 3 | Joaquin Rodriguez |
