19-09-2010: 21e etappe San Sebastián de los Reyes - Madrid 85,0 km
| Etappe uitslag |
| 1 | Tyler Farrar |
| 2 | Mark Cavendish |
| 3 | Allan Davis |
| 4 | Wouter Weylandt |
| 5 | Matthew Goss |
| 6 | Grega Bole |
| 7 | Manuel Cardoso |
| 8 | Samuel Dumoulin |
| 9 | Juan José Haedo |
| 10 | Danilo Hondo |
| 11 | Valentin Iglinskiy |
| 12 | Angelo Furlan |
| 13 | Koldo Fernandez |
| 14 | Yauheni Hutarovich |
| 15 | Enrique Mata |
| Rode trui klassement |
| 1 | Vincenzo Nibali |
| 2 | Ezequiel Mosquera |
| 3 | Peter Velits |
| Groene trui klassement |
| 1 | Mark Cavendish |
| 2 | Tyler Farrar |
| 3 | Vincenzo Nibali |
| Bolletjes trui klassement |
| 1 | David Moncoutié |
| 2 | Serafin Martinez |
| 3 | Ezequiel Mosquera |
| Witte trui klassement |
| 1 | Vincenzo Nibali |
| 2 | Ezequiel Mosquera |
| 3 | Joaquin Rodriguez |
